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(5) -Hypersensitivity reactions -Hemolysis -Nephrotoxicity (tubulointerstitial nephritis) -Kernicterus in infants Displace other drugs from albumin (e.g., warfarin) What are common toxicities Dexamethasone Topical associated with Macrolides? (4) GI discomfort, Acute cholestatic hepatitis, Eosinophilia, Skin rashes What are common toxicities associated with Tetracyclines? GI distress, Tooth discoloration and Inhibition of bone growth in children, Fanconi's syndrome, Photosensitivity What are common toxicities Dexamethasone 2mg related to Vancomycin therapy? Well tolerated in general but occasionally, Nephrotoxicity, Ototoxicity, Thrombophlebitis, Cost Of Dexamethasone diffuse flushing='Red Dexamethasone Cream Man Syndrome' What are Fluoroquinolones indicated for? (3) 1.Gram - rods of the Urinary and GI tracts (including Pseudomonas) 2.Neisseria 3. Some Gram + organisms What Topical Dexamethasone are major side effects of Dexamethasone Elixir Methicillin, Nafcillin, and Dicloxacillin? Hypersensitivity reactions What are Methicillin, Nafcillin, and Dicloxacillin used for clinically? Staphlococcus aureus What are Polymyxins used for? Resistant Gram - infections What are the Anti-TB drugs? Rifampin, Ethambutol, Streptomycin, Pyrazinamide, Isoniazid (INH) What are the clinical indications for Azole therapy? Systemic mycoses What are the clinical uses for 1st Generation Cephalosporins? Gram + cocci, Proteus mirabilis, E. coli, Klebsiella pneumoniae (PEcK) What are the clinical uses for 2nd Dexamethasone Online Generation Cephalosporins? Gram + cocci, Haemophilus influenza, Enterobacter aerogenes, Neisseria species, P. mirabilis, E. coli, K. pneumoniae, Serratia marcescens ( HEN PEcKS ) What are the clinical uses for 3rd Generation Cephalosporins? 1) Serious Gram - Dexamethasone 8 Mg infections resistant to other Beta lactams 2) Meningitis (most penetrate the BBB) What are the clinical uses for Buy Dexamethasone Aztreonam? Gram - rods: Klebsiella species, Pseudomonas species, Serratia species What are the clinical uses for Dexamethasone Inj Imipenem/cilastatin? Gram + cocci, Dexamethasone Brand Name Gram - rods, and Anerobes What are the Macrolides used for clinically? -Upper respiratory Dexamethasone 0.1 tract infections -pneumonias -STDs: Gram+ cocci (streptococcal infect in pts allergic to penicillin) -Mycoplasma, Legionella,Chlamydia, Neisseria What are the major structural differences between Penicillin and Cephalosporin? Cephalosporin: 1) has a 6 member ring attached to Dexamethasone 0.5mg the Beta lactam instead of a 5 member ring Dexamethasone Im 2)has an extra functional group ( attached to the 6 member Dexamethasone Buy ring) What are the major toxic side effects of Imipenem/cilastatin? GI distress, Skin rash, and Seizures at high plasma levels What are the major toxic side effects of the Cephalosporins? 1) Hypersensitivity reactions 2) Increased nephrotoxicity of Aminoglycosides 3) Disulfiram-like reaction with ethanol (those with a methylthiotetrazole group, e.g., cefamandole) What are the Dexamethasone Ophthalmic Solution side effects of Polymyxins? Neurotoxicity, Acute renal tubular necrosis What are the side effects of Rifampin? Minor hepatotoxicity, Drug interactions (activates P450) What are toxic side effects for Metronidazole? Disulfiram-like reaction with EtOH, Headache What Dexamethasone 2 Mg are toxicities associated with Chloramphenicol? Aplastic anemia (dose independent), Gray Baby Dexamethasone Cost Syndrome What conditions are treated with Metronidazole? Giardiasis, Amoebic dysentery (E. histolytica), Bacterial vaginitis (Gardnerella Dexamethasone Generic vaginalis), Trichomonas What do Aminoglycosides require for uptake? Oxygen What do you treat Nematode/roundworm (pinworm, whipworm) infections with? Mebendazole/Thiabendazole, Pyrantel Pamoate What drug is given for Pneumocystis carinii prophylaxis? Pentamidine What drug is used during the pregnancy of an HIV + mother?, Why? AZT, to reduce risk of Fetal Transmission What drug is used to treat Trematode/fluke (e.g., Schistosomes, Paragonimus, Clonorchis) or Cysticercosis
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